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KMID : 0361319870190010185
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Korean Journal of Medical Technologists
1987 Volume.19 No. 1 p.185 ~ p.190
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A Study of Periodic Acid Methenamine Silver(PAM) Staining in Kidney
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Abstract
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The Jones and Gomori methenamine silver methods rely on the production of aldehyde groups from the carbohydrate components of the reticular fibers and basement membranes after exposure to a periodic acid acid solution. The released aldehydes then reduce the silver of the methenamine silver complex to visible metallic silver. The gold chloride solution functions to tone the tissue section, and sodium thiosulfate functions to remove excess unreacted silver and gold.
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